Dr. Kirchhausen was appointed a Professor of Cell Biology at Harvard Medical School in 1999 and has been an investigator at The Center for Blood Research since 1992. He served as Assistant Professor, and later Associate Professor, at Harvard before attaining his present position. He received his undergraduate degree in biology from the Universidad Peruana Cayetano Heredia in 1972 and earned his Ph.D. in Biophysics from the Instituto Venezolano de Investigaciones Cientificas in 1977.

CV

download in PDF format

REFERENCES

REPRINTS:
To request a reprint, please copy the reference below and fill out this form.

1. Boll, W., Gallusser, A., and Kirchhausen, T. How do cells know which surface receptors to internalize? Biocore.

2. Mateu, L., Kirchhausen, T., Padron, R., and Camejo, G. (1977). Small-angle x-ray scattering study of human serum low-density lipoproteins with differential reactivity for an arterial proteoglycan. J Supramol Struc 7, 435-42.

3. Mateu, L., Kirchhausen, T., and Camejo, G. (1977). A low temperature structural transition in human serum low density lipoproteins. Biochim Biophys Acta 487, 243-5.

4. Mateu, L., Kirchhausen, T., and Camejo, G. (1978). Small-angle X-ray scattering and differential scanning calorimetry studies on reversibly modified human-serum low density lipoproteins. Biochemistry 17, 1436-40.

5. Kirchhausen, T., Untracht, S. H., Fless, G. M., and Scanu, A. M. (1979). Atherogenic diets and neutral-lipid organization in plasma low density lipoproteins. Atherosclerosis 33, 59-70.

6. Mateu, L., and Kirchhausen, T. (1979). Kinetics of thermal transitions in human serum low density lipoproteins (LDL) and neutral lipids. A dynamic small-angle X-ray scattering study. Acta Cientifica Venezolana 30, 478-83.

7. Kirchhausen, T., Fless, G., and Scanu, A. M. (1980). The structure of plasma low density lipoproteins: Experimental facts and interpretations--a minireview. Lipids 15, 464-7.

8. Fless, G. M., Kirchhausen, T., Fischer-Dzoga, K., Wissler, R. W., and Scanu, A. M. (1980). Relationship between the properties of the Apo B containing low-density lipoproteins (LDL) of normolipidemic rhesus monkeys and their mitogenic action on arterial smooth muscle cells groen in vitro. Atherosclerosis 5.

9. Kirchhausen, T., and Harrison, S. C. (1981). Protein organization in clathrin trimers. Cell 23, 755-761.

10. Fless, G. M., Kirchhausen, T., Fischer-Dzoga, K., Wissler, R. W., and Scanu, A. M. (1982). Serum low density lipoproteins with mitogenic effect on cultured aortic smooth muscle cells. Atherosclerosis 41, 171-83.

11. Kirchhausen, T., Harrison, S. C., Parham, P., and Brodsky, F. M. (1983). Location and distribution of the light chains in clathrin trimers. Proc Natl Acad Sci USA 80, 2481-2485.

12. Leon, V., Kirchhausen, T., Avila, E. M., and Mateu, L. (1983). Thermal effects in human plasma high density lipoproteins (HDL)3: a 13C-FT-NMR study. Acta Cientifica Venezolana 34, 209-15.

13. Hogle, J., Kirchhausen, T., and Harrison, S. C. (1983). Divalent cation sites in tomato bushy stunt viruses. J Mol Biol 171, 95-100.

14. Harrison, S. C., and Kirchhausen, T. (1983). Clathrin, cages, and coated vesicles. Cell 33, 650-2.

15. Kirchhausen, T., and Harrison, S. C. (1984). Structural domains of clathrin heavy chains. J Cell Biol 99, 1725-1734.

16. Heuser, J., and Kirchhausen, T. (1985). Deep-etch views of clathrin assemblies. J Ultrastruct Res 92, 1-27.

17. Kirchhausen, T., Wang, J. C., and Harrison, S. C. (1985). DNA gyrase and its complexes with DNA: Direct observation by electron microscopy. Cell 41, 933-943.

18. Kirchhausen, T., Harrison, S. C., and Heuser, J. (1986). Configuration of clathrin trimers: Evidence from electron microscopy. J Ultrastruct Mol Struct Res 94, 199-208.

19. Kirchhausen, T., Harrison, S. C., Chow, E. P., Mattaliano, R. J., Ramachandran, K. L., Smart, J., and Brosius, J. (1987). Clathrin heavy chain: Molecular cloning and complete primary structure. Proc Natl Acad Sci USA 84, 8805-8809.

20. Kirchhausen, T., Scarmato, P., Harrison, S. C., Monroe, J. J., Chow, E. P., Mattaliano, R. J., Ramachandran, K. L., Smart, J. E., Ahn, A. H., and Brosius, J. (1987). Clathrin light chains LCA and LCB are similar, polymorphic and share repeated heptad motifs. Science 236, 320-324.

21. Thurieau, C., Brosius, J., Burne, C., Jolles, P., Keen, J. H., Mattaliano, R. J., Chow, E. P., Ramachandran, K. L., and Kirchhausen, T. (1988). Molecular cloning and complete amino acid sequence of AP50, an assembly protein associated with clathrin-coated vesicles. DNA 7, 663-669.

22. Kirchhausen, T., Nathanson, K. L., Matsui, W., Vaisberg, A., Chow, E. P., Burne, C., Keen, J. H., and Davis, A. E. (1989). Structural and functional division into two domains of the large (100- to 115-kDa) chains of the clathrin-associated protein complex AP-2. Proc Natl Acad Sci USA 86, 2612-2616.

23. Kirchhausen, T. (1990). Identification of a putative yeast homolog of the mammalian ß chains of the clathrin-associated protein complexes. Mol Cell Biol 10, 6089-6090.

24. Matsui, W., and Kirchhausen, T. (1990). Stabilization of clathrin coats by the core of the clathrin- associated protein complex AP-2. Biochemistry 29, 10791-10798.

25. Scarmato, P., and Kirchhausen, T. (1990). Analysis of clathrin light chain-heavy chain interactions using truncated mutants of rat liver light chain LCB3. J Biol Chem 265, 3661-3668.

26. Tucker, K., Nathanson, K., and Kirchhausen, T. (1990). Sequence of the rat a c large chain of the clathrin associated protein complex AP-2. Nucleic Acids Res 18, 5306.

27. Keen, J. H., Beck, K. A., Kirchhausen, T., and Jarrett, T. (1991). Clathrin domains involved in recognition by assembly protein AP-2. J Biol Chem 266, 7950-7956.

28. Nakayama, Y., Goebl, M., O'Brine Greco, B., Lemmon, S., Pingchang Chow, E., and Kirchhausen, T. (1991). The medium chains of the mammalian clathrin-associated proteins have a homolog in yeast. Euro J Biochem 202, 569-574.

29. Kirchhausen, T., Davis, A., Frucht, S., Greco, B., Payne, G., and Tubb, B. (1991). AP17 and AP19, the mammalian small chains of the clathrin- associated protein complexes show homology to Yap17p, their putative homolog in yeast. J Biol Chem 266, 11153-11157.

30. Gallusser, A., and Kirchhausen, T. (1993). The b1 and b2 subunits of the AP complexes are the clathrin coat assembly components. EMBO J 12, 5237-5244.

31. Kirchhausen, T. (1993). Coated pits and coated vesicles - sorting it all out. Curr Opin Struc Biol 3, 182-188.

32. Kirchhausen, T., and Toyoda, T. (1993). Immunoelectron microscopic evidence for the extended conformation of light chains in clathrin trimers. J Biol Chem 268, 10268-10273.

33. Kirchhausen, T., Staunton, D. E., and Springer, T. A. (1993). Location of the domains of ICAM-1 by immunolabeling and single-molecule electron microscopy. J Leukocyte Biol 53, 342-346.

34. Osborn, L., Vassallo, C., Griffiths Browning, B., Tizard, R., Haskard, D. O., Benjamin, C. D., Dougas, I., and Kirchhausen, T. (1994). Arrangement of domains, and amino acid residues required for binding of vascular cell adhesion molecule-1 to its counter-receptor VLA-4 (alpha4beta1). J Cell Biol 124, 601-608.

35. Pahn, H. L., Finlay, J. A., Chu, D. S., Tan, P., Kirchhausen, T., and Payne, G. S. (1994). The Saccharomyces cerevisiae APS1 gene encodes a homologue of the small subunit of the mammalian clathrin AP-1 complex: Evidence for functional interaction with clathrin at the Golgi complex. EMBO J 13, 1706-1717.

36. Søgaard, M., Tani, K., Ye, R., Geromanos, S., Tempst, P., Kirchhausen, T., Rothman, J. E., and Sollner, T. (1994). A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell 78, 937-948.

37. Boll, W., Gallusser, A., and Kirchhausen, T. (1995). Role of the regulatory domain of the EGF-receptor cytoplasmic tail in selective binding of the clathrin-associated complex AP-2. Curr Biol 5, 1168-1178.

38. Ohno, H., Stewart, J., Fournier, M. C., Bosshart, H., Rhee, I., Miyatake, S., Saito, T., Gallusser, A., Kirchhausen, T., and Bonifacino, J. S. (1995). Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science 269, 1872-1875.

39. Ohno, H., Kirchhausen, T., and Bonifacino, J. S. (1995). Recognition of tyrosine-based sorting signals by the medium chains of clathrin- associated protein complexes. J NIH Res 7, 50-51.

40. Rad, M. R., Phan, H. L., Kirchrath, L., Tan, P. K., Kirchhausen, T., Hollenberg, C. P., and Payne, G. S. (1995). Saccharomyces cerevisiae Apl2p, a homologue of the mammalian clathrin AP ß subunit, plays a role in clathrin-dependent Golgi functions. J Cell Sci 108, 1605-15.

41. Shih, W., Gallusser, A., and Kirchhausen, T. (1995). A clathrin-binding site in the hinge of the b-2 chain of mammalian AP-2 complexes. J Biol Chem 270, 31083-31090.

42. Sorkin, A., McKinsey, T., Shih, W., Kirchhausen, T., and Carpenter, G. (1995). Stoichiometric interaction of the epidermal growth factor receptor with the clathrin-associated protein complex AP-2. J Biol Chem 270, 619-625.

43. Speelman, B. A., Allen, K., Grounds, T. L., Neutra, M. R., Kirchhausen, T., and Wilson, J. M. (1995). Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells. J Biol Chem 270, 1583-1588.

44. Stepp, J. D., A., P.-P., Hamilton, S., Kirchhausen, T., and Lemmon, S. K. (1995). A late Golgi sorting function from sacharomyces cerevisiae Apm1p, but not for Apm2p, a second yeast clathrin AP medium chain-related protein. Mol Biol Cell 6, 41-58.

45. Boll, W., Ohno, H., Songyang, Z., Rapoport, I., Cantley, L. C., Bonifacino, J. S., and Kirchhausen, T. (1996). Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes. EMBO J 15, 5789-5795.

46. Bunnell, S. C., Henry, P. A., Kolluri, R., Kirchhausen, T., Rickles, R. J., and Berg, L. J. (1996). Identification of Itk/Tsk SH3 domain ligands. J Biol Chem 271, 25646-25656.

47. Kirchhausen, T., and Rosen, F. S. (1996). Disease mechanism: Unraveling Wiskott-Aldrich syndrome. Curr Biol 6, 676-678.

48. Kirchhausen, T. (1996). Always carry a spare coat. Trends Cell Biol 6, 380.

49. Kolluri, R., Fuchs Tolias, K., Carpenter, C. L., Rosen, F. S., and Kirchhausen, T. (1996). Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42. Proc Natl Acad Sci USA 93, 5615-5618.

50. Spiro, D. J., Boll, W., Kirchhausen, T., and Wessling-Resnick, M. (1996). Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro. Mol Biol Cell 7, 355-367.

51. Tebar, F., Sorkina, T., Sorkin, A., Ericsson, M., and Kirchhausen, T. (1996). Eps15 is a component of clathrin-coated pits and vesicles and is located at the rim of coated pits. J Biol Chem 271, 28727-28730.

52. Bonifacino, J. S., Marks, M. S., Ohno, H., and Kirchhausen, T. (1996). Mechanisms of signal-mediated protein sorting in the endocytic and secretory pathways. Proc Assoc Am Phys 108, 285-295.

53. Spiro, D. J., Boll, W., Kirchhausen, T., and Wessling-Resnick, M. (1996). Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro. Mol Biol Cell 7, 355-367.

54. Marks, M. S., Ohno, H., Kirchhausen, T., and Bonifacino, J. S. (1997). Protein sorting by tyrosine-based signals: Adapting to the Ys and wherefores. Trends Cell Biol 7, 124-128.

55. Rapoport, I., Miyazaki, M., Boll, W., Duckworth, B., Cantley, L. C., Shoelson, S., and Kirchhausen, T. (1997). Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes. EMBO J 16, 2240-2250.

56. Clairmont, K. B., Boll, W., Ericsson, M., and Kirchhausen, T. (1997). A role for the hinge/ear domain of the beta chains in the incorporation of AP complexes into clathrin-coated pits and coated vesicles. Cellular & Molecular Life Sciences 53, 611-619.

57. Kirchhausen, T., Pines, J., Toldo, L., and Lafont, F. (1997). Membranes and Sorting Membrane Permeability. Current Opinion in Cell Biology 9, 473.

58. Kirchhausen, T., Bonifacino, J. S., and Riezman, H. (1997). Linking cargo to vesicle formation - receptor tail interactions with coat proteins. Current Opinion in Cell Biology 9, 488-495.

59. Cupers, P., ter Haar, E., Boll, W., and Kirchhausen, T. (1997). Parallel dimers and anti-parallel tetramers formed by epidermal growth factor receptor pathway substrate clone 15. J Biol Chem 272, 33430-4.

60. Tong, X., Boll, W., Kirchhausen, T., and Howley, P. M. (1998). Interaction of the bovine papillomavirus E6 protein with the clathrin adaptor complex AP-1. J Virol 72, 476-82.

61. Kamiguchi, H., Long, K. E., Pendergast, M., Schaefer, A. W., Rapoport, I., Kirchhausen, T., and Lemmon, V. (1998). The Neural Cell Adhesion Molecule L1 Interacts With the AP-2 Adaptor and Is Endocytosed Via the Clathrin-Mediated Pathway. Journal of Neuroscience 18, 5311-5321.

62. DeTulleo, L., and Kirchhausen, T. (1998). The clathrin endocytic pathway in viral infection. EMBO J 17, 4585-4593.

63. Cupers, P., Jadhav, A. P., and Kirchhausen, T. (1998). Assembly of clathrin coats disrupts the association between Eps15 and AP-2 adaptors. J Biol Chem 273, 1847-1850.

64. Rapoport, I., Chen, Y. C., Cupers, P., Shoelson, S. E., and Kirchhausen, T. (1998). Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site. EMBO J 17, 2148-55.

65. Ter Haar, E., Musacchio, A., Harrison, S. C., and Kirchhausen, T. (1998). Atomic Structure of Clathrin - a b Propeller Terminal Domain Joins an a Zigzag Linker. Cell 95, 563-573.

66. Greenberg, M., Detulleo, L., Rapoport, I., Skowronski, J., and Kirchhausen, T. (1998). A Dileucine Motif in HIV-1 Nef Is Essential For Sorting Into Clathrin-Coated Pits and For Downregulation of CD4. Current Biology 8, 1239-1242.

67. Kirchhausen, T. (1998). Vesicle Formation - Dynamic Dynamin Lives Up to Its Name. Current Biology 8, R 792-R 794.

68. Sanderfoot, A. A., Ahmed, S. U., Marty-Mazars, D., Rapoport, I., Kirchhausen, T., Marty, F., and Raikhel, N. V. (1998). A putative vacuolar cargo receptor partially colocalizes with AtPEP12p on a prevacuolar compartment in Arabidopsis roots. PNAS 95, 9920-9925.

69. Kirchhausen, T. (1998). Wiskott-Aldrich syndrome: a gene, a multifunctional protein and the beginnings of an explanation. Molecular Medicine Today 4, 300-304.

70. Schneider, H., Martin, M., Agarraberes, F. A., Yin, L., Rapoport, I., Kirchhausen, T., and Rudd, C. E. (1999). Cytolytic T lymphocyte-associated antigen-4 and the TCR zeta/CD3 complex, but not CD28, interact with clathrin adaptor complexes AP-1 and AP-2. J. Immunology 163, 1868-1879.

71. Musacchio, A., Smith, C. J., Roseman, A. M., Harrison, S. C., Kirchhausen, T., and Pearse, B. M. F. (1999). Functional organization of clathrin in coats: Combining electron cryomicroscopy and x-ray crystallography. Molecular Cell 3, 761-770.

72. Rohatgi, R., Ma, L., Miki, H., Lopez, M., Kirchhausen, T., Takenawa, T., and Kirschner, M. W. (1999). The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell 97, 221-231.

73. Kirchhausen, T. (1999). Cell biology - Boa constrictor or rattlesnake? Nature 398, 470-471.

74. Kirchhausen, T. (1999). Adaptors for clathrin mediated traffic. Annu. Rev. Cell Dev. Biol. 15, 705-732.

75. Jones, A. T., Spiro, D. J., Kirchhausen, T., Melancon, P., and Wessling-Resnick, M. (1999). Studies on the inhibition of endosome fusion by GTP gamma S-bound ARF. Journal of Cell Science 112, 3477-3485.

76. Ter Haar, E., Harrison, S. C., and Kirchhausen, T. (2000). Peptide-in-groove interactions link target proteins to the b-propeller of clathrin. Proc. Natl. Acad. Sci. USA 97, 1096-1100.

77. Kirchhausen, T. (2000). Clathrin. Ann. Rev. Biochem. 69, 699-727.

78. Farr, G. W., Furtak, K., Rowland, M. B., Ranson, N. A., Saibil, H. R., Kirchhausen, T., and Horwich, A. L. (2000). Multivalent binding of nonnative substrate proteins by the chaperonin GroEL. Cell 100, 561-573.

79. Kirchhausen, T. (2000). Three ways to make a vesicle [Review]. Nature Reviews Molecular Cell Biology 1, 187-198.

80. Chen, F., Ma, L., Parrini, M. C., Mao, X., Lopez, M., Wu, C., Marks, P. W., Davidson, L., Kwiatkowski, D. J., Kirchhausen, T., Orkin, S. H., Rosen, F. S., Mayer, B. J., Kirschner, M. W., and Alt, F. W. (2000). Cdc42 is required for PIP2-induced actin polymerization and early development but not for cell viability. Current Biology 10, 758-765.

81. Pelish, H. E., Westwood, N. J., Feng, Y., Kirchhausen, T., and Shair, M. D. (2001). Use of biomimetic diversity-oriented synthesis to discover
galanthamine-like molecules with biological properties beyond those of the natural product. Journal of the American Chemical Society 123, 6740-6741.

82. Lederkremer, G., Cheng, Y., Petre, B., Vogan, E., Springer, S., Schekman, R., Walz, T., and Kirchhausen, T. (2001). Structure of the Sec23p/24p and Sec13p/31p complexes of COPII. Proc. Natl. Acad. Sci. 98, 10704-10709.

83. Kirchhausen, T. (2002). Single-handed recognition of a sorting traffic motif by the GGA proteins. Nature Structural Biology 9, 241-244.

84. Boll, W., Rapoport, I., Brunner, C., Modis, Y., Prehn, S., and Kirchhausen, T. (2002). The mu 2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppO sorting signals at distinct sites, Traffic, 3, 590-600.

85. Kirchhausen, T. (2002). Clathrin adaptors really adapt [Review], Cell, 109, 413-416.

86. Schaefer, A. W., Kamei, Y., Kamiguchi, H., Wong, E. V., Rapoport, I., Kirchhausen, T., Beach, C. M., Landreth, G., Lemmon, S. K. & Lemmon, V. (2002). L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1. J Cell Biology, 157, 1223-1232.

87. Boes, M., Cerny, J., Massol, R., Op den Brouw, M., Kirchhausen, T., Chen, J. Z., and Ploegh, H. L. (2002). T-cell engagement of dendritic cells rapidly rearranges MHC class II transport, Nature 418, 983-988.

88. Nieland, T., Penman, M., Dori, L., Krieger, M. and Kirchhausen, T. (2002). Discovery of novel chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI, PNAS 99, 15422-7.

89 . Legesse-Miller, A., H. Massol, R. and Kirchhausen, T. (2003) Constriction and Dnm1p recruitment are distinct processes in mitochondrial fission MBC 14, 1953-1963.

90. Feng Y, Yu S, Lasell TK, Jadhav AP, Macia E, Chardin P, Melancon P, Roth M, Mitchison T, Kirchhausen T. (2003) Exo1: A new chemical inhibitor of the exocytic pathway. Proc Natl. Acad. Sci. 100, 6469-6474.

91 . Wang, Y., Wang, J., Sun, H., Martinez, M., Sun, Y., Macia, E., Kirchhausen, T., Albanesi, J., Roth, M. and Yin, H.(2003) Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi, Cell, 114, 299-310.

92 . Chandran, K., Parker, J., Ehrlich, M. Kirchhausen, T., and Nibert, M.(2003) The _ region of outer-capsid protein _1 undergoes conformational change and release from reovirus particles during cell entry, Journal of Virology, 77, 13361-75.

93. Yarrow, J.C., Feng, Y., Perlman, Z. E., Kirchhausen, T., and Mitchison, T.J.(2003) Phenotypic screening of small molecule libraries by high throughput cell imaging. Comb Chem High Throughput Screen, 6, 279-86.

94 . Larsen, J., Massol, R., Nieland, T. and Kirchhausen, T.(2004) HIV Nef-mediated MHC class I down-modulation is independent of Arf6 activity. Molecular Biology of the Cell 15, 323-331.

95. Nieland, T., Chroni, A., Fitzgerald, M., Maliga, Z., Zannis, V., Kirchhausen, T., and
Krieger, M.(2004) Cross-inhibition of SR-BI-and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J Lipid Res 45, 1256-1265.

96. Massol, R., Larsen, J., Fujinaga, Y., Lencer, W., Kirchhausen, T.(2004) Chloera Toxin does not require functional Arf6- and dynamin-dependent endocytic pathways. Molecular Biology of the Cell, 15, 323-331.

97. Nieland, T.J., Feng. Y., Brown, J., Buckett, P., McGraw, T., Kirchhausen, T., Wessling-Resnick,
M.(2004) Chemical Genetic Screening Identifies Sulfonamides That Raise Organellar pH and Interfere with Membrane Traffic. Traffic 5, 478-492.

98. Feng, Y., Jadhav, P., Rodighiero, C., Fujinaga, Y., Kirchhausen, T., Lencer W.(2004) Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells. EMBO Rep 5, 596-601.

99. Boll, W., Ehrlich, M., Collier, R., Kirchhausen, T.(2004) Effects of dynamin
inactivation on pathways of anthrax toxin uptake. EJCB 83, 281-288.

100. Ehrlich, M. Boll, W., Van Oijen, A., Hariharan, R., Chandran, K., Nibert, M.(2004) Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell 118, 591-605.

101. Cerny, J. Feng, Y., Yu, A., Miyake, K., Borgonovo, B., Klumperman, J., Meldolesi, J., McNeil, P.L., and Kirchhausen, T. (2004) The small chemical vacuolin-1 inhibits Ca (2+)- dependent lysosomal exocytosis but not cell resealing. EMBO Rep 5, 883-888.

102. Heldwein, E., Macia, E., Wang, J., Yin, H., Kirchhausen, T., and Harrison, S.(2004) Crystal structure of the clathrin adaptor AP-1 core. PNAS 101, 14108-14113.

103.Fotin, A., Cheng, Y., Sliz, P., Grigorieff, N., Harrison, S., Kirchhausen, T., Waltz, T.,(2004) Molecular model for complete clathrin lattice from electron cryomicroscopy. Nature 432, 573-579.

104. Fotin, A., Chen, Y., Grigorieff, N., Waltz, T., Harrison, S., Kirchhausen, T., (2004) Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature 432, 649-653.

105. Kirchhausen, T., Boll. W., van Oijen, A., and Ehrlich, M. (2005). Lipids, Rafts and Traffic: – Single-molecule live-cell imaging of clathrin-based endocytosis. Biochem Soc Symp, 71-76.

106. Benedito, A., Lehtinen, M., Massol, R., Kirchhausen, T., Rao, A., and Bonni, A. (2005) The transcription factor NFAT3 mediates neuronal survival. JBC 280, 2818-2825.

107. Nieland, T., Ehrlich,M. Krieger, M., Kirchhausen, T., (2005) Endocytosis is not required for selective lipid uptake by murine SR-BI. BBA-Molecular and Cell Biology of Lipids 1734, 44-51.

108. Massol, R., Larsen, J., Kirchhausen, T. (2005) Possible role of deep tubular invaginations of the plasma membrane in MHC-I trafficking. ECR 306, 142-149.

109. McNeil, P., Kirchhausen, T., (2005) An Emergency Response Team for Membrane Repair [Review], Nat. Rev. Mol. Cell Bio. 6, 499 –504.

110. Paleotti, O., Macia, E., Luton, F., Klein, S., Partisani, M., Chardin, P., Kirchhausen, T., and Franco, M. (2005) The small G-protein ARF6GTP recruits the AP-2 adaptor complex to membranes. JBC 280, 2818-2825.